| Methods |
Design: randomised double‐blind double‐dummy parallel study, used drawing lots.
Device: Turbuhaler vs pMDI alone
Drug: terbutaline
Dose: 0.5mg (both devices)
Duration: 10 min |
| Participants |
118 children, age range 8‐15, mean age 11.3. FEV1 was <70% predicted. |
| Interventions |
Pulmonary function testing done 10 min post dose. |
| Outcomes |
Change from baseline FEV1, FVC and Vmax50%. |
| Notes |
Author reply used drawing lots for allocation concealment and provided further details on the process of double‐blinding. |
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Allocation concealment? |
Low risk |
Study investigators were not aware as to order to treatment group assignment (Cochrane Grade A) |
