Table 2.
MIC values with acrB and oqxB complementation in E. coli C43(DE3)ΔacrB.
| Compounds | E. coli C43(DE3) | ΔacrB | ΔacrB + pET21a | ΔacrB + acrB | ΔacrB + oqxB |
|---|---|---|---|---|---|
| Linezolid# | 200 | 12.5 | 12.5 | 100 | 200 |
| Novobiocin# | 400 | 12.5 | 12.5 | 400 | 100 |
| Ciprofloxacin* | 6.25 | 6.25 | 6.25 | 6.25 | 100 |
| Levofloxacin* | 6.25 | 12.5 | 6.25 | 12.5 | 100 |
| Moxifloxacin* | 6.25 | 12.5 | 12.5 | 25 | 200 |
| Rifampicin# | 5 | 5 | 5 | 5 | 5 |
#MIC values in µg/mL.
*MIC values in ng/mL.
E. coli C43(DE3) or its ΔacrB strain used for MIC.
pET21a, +acrB, or +oqxB: complementation with a plasmid carrying the respective genes.
(Refer to Supplementary data for further details of the strains and constructs).