Table 2.
Summary of changes in cardiac magnetic resonance-derived cardiac indexes, clinical and laboratory parameters.
| All (n = 40) | AVF flow ≥ 600 mL/min (n = 22) | AVF flow < 600 mL/min (n = 18) | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Baseline | Follow-up | p value | Baseline | Follow-up | p value | Baseline | Follow-up | p value | |
| LV mass, g | 154.4 ± 52.6a | 161.8 ± 50.2 | 0.02 | 152.4 ± 55.6a | 168.0 ± 55.6 | < 0.001 | 156.9 ± 50.2 | 154.4 ± 43.0 | 0.52 |
| LV mass index, g/m2 | 83.7 ± 27.1 | 88.8 ± 26.2 | 0.005 | 80.8 ± 24.7 | 90.3 ± 24.7 | < 0.001 | 87.3 ± 30.2 | 87.0 ± 28.6 | 0.91 |
| LV end-diastolic volume, mL | 155.8 ± 55.1 | 165.3 ± 49.6 | 0.04 | 167.5 ± 58.7 | 182.0 ± 54.5 | 0.03 | 141.5 ± 48.2 | 145.0 ± 34.2 | 0.61 |
| LV end-systolic volume, mL | 51.3 ± 27.6 | 55.4 ± 27.1 | 0.12 | 57.2 ± 31.7 | 63.5 ± 32.8 | 0.10 | 44.1 ± 20.0 | 45.5 ± 13.0 | 0.70 |
| LV ejection fraction, % | 67.9 ± 7.8 | 67.1 ± 7.2 | 0.52 | 66.7 ± 8.1 | 66.1 ± 7.4 | 0.66 | 69.2 ± 7.6 | 68.4 ± 7.0 | 0.65 |
| LV cardiac output, L/min | 6.9 ± 2.1 | 7.5 ± 2.0 | 0.02 | 7.2 ± 1.9 | 8.2 ± 1.9 | 0.007 | 6.5 ± 2.2 | 6.8 ± 1.8 | 0.61 |
| LV cardiac index, L/min/m2 | 3.8 ± 1.1 | 4.2 ± 1.1 | 0.009 | 3.9 ± 1.0 | 4.5 ± 1.2 | 0.002 | 3.6 ± 1.1 | 3.8 ± 0.9 | 0.53 |
| LV global longitudinal strain, % | − 15.3 ± 2.3 | − 15.7 ± 2.5 | 0.21 | − 15.9 ± 1.9 | − 16.0 ± 2.0 | 0.93 | − 14.5 ± 2.6 | − 15.2 ± 3.1 | 0.04 |
| LA volume, mL | 85.9 ± 40.1 | 93.4 ± 34.7 | 0.10 | 86.6 ± 43.3 | 99.3 ± 37.8 | 0.05 | 84.9 ± 37.0 | 86.2 ± 30.1 | 0.85 |
| LA volume index, mL/m2 | 46.9 ± 21.0 | 52.1 ± 20.0 | 0.04 | 46.6 ± 21.9 | 54.5 ± 19.9 | 0.03 | 47.3 ± 20.6 | 49.2 ± 20.4 | 0.59 |
| Septal thickness, mm | 9.0 ± 2.9 | 8.5 ± 2.9 | 0.33 | 8.5 ± 2.9 | 7.8 ± 3.0 | 0.23 | 9.5 ± 2.9 | 9.5 ± 2.6 | 0.90 |
| Body weight, kg | 74.7 ± 16.7 | 73.3 ± 15.2 | 0.74 | 75.3 ± 17.2 | 73.6 ± 15.2 | 0.76 | 73.9 ± 16.7 | 73 ± 15.7 | 0.89 |
| Systolic BP, mmHg | 154.3 ± 29.8 | 147 ± 30.0 | 0.35 | 149.8 ± 24.0 | 146.2 ± 21.1 | 0.64 | 160.1 ± 36.3 | 148.2 ± 39.7 | 0.43 |
| Diastolic BP, mmHg | 76.3 ± 13.9 | 69.4 ± 10.5 | 0.03 | 77.3 ± 14.9 | 70.2 ± 12.2 | 0.14 | 74.9 ± 12.9 | 68.4 ± 8.0 | 0.13 |
| Hematocrit, % | 32.7 ± 5.2 | 32.4 ± 4.3 | 0.85 | 32.0 ± 4.5 | 31.5 ± 4.0 | 0.70 | 33.4 ± 5.9 | 33.6 ± 4.5 | 0.93 |
| Serum creatinine, μmol/Lb | 458 ± 127 | 487 ± 161 | 0.53 | 486 ± 140 | 521 ± 180 | 0.57 | 394 ± 56 | 408 ± 53 | 0.65 |
| Estimated GFR, mL/min/1.73 m2b | 11.5 ± 2.6 | 10.3 ± 4.0 | 0.25 | 11.1 ± 2.3 | 9.5 ± 4.3 | 0.26 | 12.6 ± 3.0 | 11.9 ± 2.6 | 0.71 |
| NT-proBNP, pg/mL | 2390 ± 2513 | 3114 ± 2360 | 0.08 | 1647 ± 1401 | 3174 ± 2439 | 0.02 | 2948 ± 3043 | 3069 ± 2408 | 0.82 |
| hs-cTnI, pg/mL | 13.1 ± 11.2 | 12.0 ± 9.1 | 0.36 | 12.4 ± 12.1 | 12.7 ± 8.9 | 0.89 | 13.7 ± 10.9 | 11.4 ± 9.6 | 0.21 |
AVF arteriovenous fistula, LA left atrial, LV left ventricular, BP blood pressure, GFR glomerular filtration rate calculated using Chronic Kidney Disease Epidemiology Collaboration (CKD EPI) formula, NT-proBNP N-Terminal-pro B-type Natriuretic Peptide, hs-cTnI high-sensitivity cardiac Troponin I.
aPlus-minus values are mean ± SD.
bIncludes 23 non-dialysis participants.