Table 1.
Temporal changes of muscle strength and laboratory test results in the patient
| 0 months
(presentation) |
6 m | 12 m | 17 m
(just before ASCT) |
19 m
(2 m after ASCT) |
20 m | 22 m | |
| Body weight, kg | 42.5 | 41.0 | 41.7 | 39.8 | 39.4 | NT | 44.0 |
| Grip strength, kg | |||||||
| Right | 17 | 20 | 14 | NT | 11 | 14 | 17 |
| Left | 22 | 20 | 15 | NT | 15 | 15 | 16 |
| MRC scale | |||||||
| Shoulder abduction | 2 | 2 | 2 | NT | 2 | 3 | 3 |
| Hip flexion | 2 | 2 | 2 | NT | 2 | 2 | 2 |
| Pulmonary function test | |||||||
| FVC, L | 2.23 | 2.08 | 1.80 | 1.84 | 1.61 | NT | 1.84 |
| Ratio of FVC to
predicted value, % |
84.3 | 79.2 | 69.1 | 70.5 | 61.7 | NT | 70.5 |
| FEV1, L | 2.06 | 1.82 | 1.59 | 1.65 | 1.47 | NT | 1.61 |
| CK, U/L | 119 | 69 | 75 | 71 | 46 | 115 | 141 |
| Creatinine, mg/dL | 0.30 | 0.27 | 0.24 | 0.28 | 0.29 | 0.29 | 0.30 |
ASCT: autologous stem-cell transplantation
MRC: Medical Research Council
FVC: forced vital capacity
FEV1: forced expiratory volume in one second
CK: creatine kinase
NT: not tested