Table 2.
Factor V Leiden mutation
| Variable | Frequency % (n) | |
| Factor V Leiden mutation (n=482) | ||
| Positive | 4.4 (21) | |
| Negative | 95.6 (461) | |
| Distribution of Socio Demographics and Clinical Characteristics among Positive FVL Mutations (n=21) | ||
| Variable | Frequency % | (p-value) |
| Zygosity | ||
| Heterozygous | 95.2 (20) | |
| Homozygous | 4.8 (1) | |
| Gender | 0.037 | |
| Female | 57.1(12) | |
| Male | 42.9(9) | |
| Nationality | <0.001 | |
| Saudi | 33.3(7) | |
| Non-Saudi | 66.7(14) | |
| Comorbidities | ||
| Diabetes Mellitus | 14.3 (3) | 0.866 |
| Hypertension | 9.5 (2) | 0.946 |
| Dyslipidemia | 14.3 (3) | 0.065 |
| Anemia | 0 (0) | 0.435 |
| PCOS (N=12) | 8.3 (1) | 0.535 |
| Hypothyroidism | 4.8(1) | 0.305 |
| Clinical Manifestation | ||
| DVT | 47.6(10) | 0.025 |
| PE | 0(0) | 0.133 |
| Stroke | 14.3(3) | 0.936 |
| Miscarriage (n=12) | ||
| 0(0) | 0.002 | |
| Body Mass index (N=17) | 0.009 | |
| Underweight (less than 18) | 5.9 (1) | |
| Normal (18.5–24.9) | 11.8 (2) | |
| Overweight (25–29.9) | 23.5 (4) | |
| Class 1 Obesity (30–34.9) | 17.6 (3) | |
| Class 2 Obesity (35–39.9) | 23.5 (4) | |
| Morbid Obesity (>40) | 17.6 (3) | |
| Variable | Mean (sd) | |
| Age | 37.48 (13.69) | |
| Minimum 8 years | ||
| Maximum 61 years | ||