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. 2021 Aug;83(3):407–417. doi: 10.18999/nagjms.83.3.407

Table 2.

Factor V Leiden mutation

Variable Frequency % (n)
Factor V Leiden mutation (n=482)
Positive 4.4 (21)
Negative 95.6 (461)
Distribution of Socio Demographics and Clinical Characteristics among Positive FVL Mutations (n=21)
Variable Frequency % (p-value)
Zygosity
Heterozygous 95.2 (20)
Homozygous 4.8 (1)
Gender 0.037
Female 57.1(12)
Male 42.9(9)
Nationality <0.001
Saudi 33.3(7)
Non-Saudi 66.7(14)
Comorbidities
Diabetes Mellitus 14.3 (3) 0.866
Hypertension 9.5 (2) 0.946
Dyslipidemia 14.3 (3) 0.065
Anemia 0 (0) 0.435
PCOS (N=12) 8.3 (1) 0.535
Hypothyroidism 4.8(1) 0.305
Clinical Manifestation
DVT 47.6(10) 0.025
PE 0(0) 0.133
Stroke 14.3(3) 0.936
Miscarriage (n=12)
0(0) 0.002
Body Mass index (N=17) 0.009
Underweight (less than 18) 5.9 (1)
Normal (18.5–24.9) 11.8 (2)
Overweight (25–29.9) 23.5 (4)
Class 1 Obesity (30–34.9) 17.6 (3)
Class 2 Obesity (35–39.9) 23.5 (4)
Morbid Obesity (>40) 17.6 (3)
Variable Mean (sd)
Age 37.48 (13.69)
Minimum 8 years
Maximum 61 years