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. 2021 Sep 13;12:5395. doi: 10.1038/s41467-021-25403-y

Fig. 5. CLL subtype, genetic markers, and treatment outcome in CLL8.

Fig. 5

a PFS (left) and OS (right) according to treatment arm (FC: dotted line; FCR: continuous line) and subtype (color-coded) (n = 319). CLL subtype color code defined in Fig. 5a applies for Fig. 5a, b. b PFS (left) and OS (right) according to the IGHV mutation status and subtype (color-coded) (both treatment arms) (n = 310). c PFS according to subtypes; GI (dark blue) and (I)EMT-L (light blue), TP53, and ATM mutation and/or deletion status (shown for all cases and individual treatment arms) (n = 147). CLL subtype color code defined in Fig. 5c applies for Fig. 5c, d. d PFS in TP53 wild-type cases according to SF3B1 mutation status for GI (dark blue) or (I)EMT-L (light blue) (n = 193). For Fig. 5a–d, the log-rank test was used to compare the survival distributions. Data within individual figures derives from biologically independent samples.