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. 2021 Sep 13;11:18174. doi: 10.1038/s41598-021-97566-z

Table 2.

Univariate analysis of demographics and clinical characteristics.

Variable N Events Median months 1-Year survival % (95% CI) log-rank p value Cox univariate hazard ratio (95% CI) Cox univariate Wald p-value
Sex 0.023
Female 259 157 (61%) 13.4 58.4 (52.3, 64.5)
Male 262 178 (68%) 11.1 48.6 (42.4, 54.8) 1.28 (1.03, 1.59) 0.024
Race 0.75
Non-white 82 51 (62%) 12.3 52.0 (40.9, 63.1)
White 439 284 (65%) 12.7 53.8 (49.0, 58.5) 0.95 (0.71, 1.28) 0.75
Age 0.005
< 65 307 186 (61%) 13.8 56.8 (51.1, 62.4)
≥ 65 214 149 (70%) 10.5 48.8 (42.0, 55.6) 1.36 (1.10, 1.69) 0.005
KPS < 0.001
< 90 221 157 (71%) 8.9 40.8 (34.2, 47.4) 1.97 (1.55, 2.50) < 0.001
≥ 90 220 119 (54%) 18.4 66.8 (60.5, 73.1)
Missing 80 59 (74%) 12.1 51.3 (40.0, 62.6) 1.65 (1.21, 2.26) 0.002
Lesion number 0.49
1 258 160 (62%) 13.3 55.7 (49.4, 61.9)
≥ 2 261 173 (66%) 12.3 51.4 (45.2, 57.6) 1.08 (0.87, 1.34) 0.49
SRS < 0.001
0–1 345 245 (71%) 9.8 43.4 (38.1, 48.8)
≥ 2 164 82 (50%) 21.7 75.1 (68.4, 81.8) 0.45 (0.35, 0.58) < 0.001
Histology < 0.001
Other 131 100 (76%) 9.1 38.7 (30.1, 47.3)
Adenocarcinoma 371 221 (60%) 15.0 58.4 (53.3, 63.5) 0.57 (0.45, 0.72) < 0.001
EC-mets 0.018
No 273 166 (61%) 13.9 57.7 (51.7, 63.6)
Yes 238 162 (68%) 10.5 47.9 (41.4, 54.5) 1.30 (1.04, 1.61) 0.018
WBRT 0.11
No 390 248 (64%) 12.2 51.0 (45.9, 56.1)
Yes 131 87 (66%) 14.9 60.7 (52.3, 69.1) 0.82 (0.64, 1.05) 0.11
Age 521 335 (64%) 12.7 53.5 (49.1, 57.8) 1.014 (1.003, 1.025) 0.012
KPS 441 276 (63%) 12.7 53.8 (49.1, 58.6) 0.96 (0.95, 0.97) < 0.001
Lesion number 519 333 (64%) 12.7 53.5 (49.1, 57.9) 0.99 (0.96, 1.03) 0.72
SRS 509 327 (64%) 12.7 53.8 (49.4, 58.2) 0.65 (0.57, 0.75) < 0.001

Significant differences (p < 0.05) are bolded.