Fig. 1. Adverse myocardial remodeling in the rat model of myocardial infarction (MI).
A Left: experimental protocols of control (n = 10), MI 1-week (n = 13), MI 2-week (n = 10), and MI 4-week (n = 15) groups. Right: wheat germ agglutinin (WGA) staining and Masson’s trichrome staining were carried out with the tissue at the location indicated by the dotted line. B Representative cardiac slices of rats with infarcts stained by 2,3,5-triphenyl tetrazolium chloride (TTC) in the control and MI 1-week groups. C Cardiomyocyte cross-sectional areas were examined using WGA staining (scale bar = 50 µm). D Myocardial fibrosis was examined using Masson’s trichrome staining (scale bar = 1 mm). **P < 0.01.