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. 2021 Aug 31;9:723817. doi: 10.3389/fcell.2021.723817

FIGURE 4.

FIGURE 4

The relationship between the ICI score and somatic mutation in the TCGA- BLCA cohort. (A) TMB difference in the high and low ICI score subgroups (Wilcoxon test, p = 0.002). (B) Pearson correlation analysis between ICI score and mutation load (Pearson correlation coefficient = 0.157, p = 0.001). (C) The comparison of TMB among three gene clusters (Kruskal–Wallis test, p = 0.0002). (D) Kaplan–Meier curves for high and low TMB groups of (log-rank test, p < 0.001). (E) Kaplan–Meier curves for patients stratified by both TMB and ICI score (log-rank test, p < 0.001).