TABLE 1.

The association between ICI score and somatic variants.

Hugo_Symbol	High score		Low score		p-value
	Mutated samples	Mutation frequency	Mutated samples	Mutation frequency
FGFR3	36	19%	20	9%	0.0042
NEB	33	17%	20	9%	0.0139
PIK3CA	51	27%	38	18%	0.0214
SYNE1	47	25%	35	16%	0.0287
KDM6A	57	30%	49	23%	0.0829
TTN	98	52%	94	43%	0.0858
RB1	39	21%	31	14%	0.0912
MUC16	61	32%	54	25%	0.0993
STAG2	31	16%	24	11%	0.1167
TP53	98	52%	96	44%	0.1256
BIRC6	28	15%	23	11%	0.2011
FLG	36	19%	32	15%	0.2470
ATM	30	16%	26	12%	0.2567
AHNAK2	27	14%	23	11%	0.2595
HMCN1	39	21%	36	17%	0.2948
KMT2D	58	31%	57	26%	0.3241
KMT2C	39	21%	37	17%	0.3557
EP300	32	17%	31	14%	0.4627
ARID1A	44	23%	57	26%	0.4874
CSMD3	28	15%	29	13%	0.5774
OBSCN	26	14%	27	12%	0.6950
ELF3	22	12%	27	12%	0.8045
DNAH11	25	13%	28	13%	0.9229
DNAH5	25	13%	28	13%	0.9229
MACF1	32	17%	36	17%	0.9268