TABLE 5.
Dynamic treatment regimes (decision rules: R=reflexology; MP=meditative practices): least square means over weeks 5–12 and their SEs, adjusted for baseline and balancing factors used in randomization
| Dynamic treatment regime | (R, R) | (R, MP) | (MP, R) | (MP, MP) | ||||
|---|---|---|---|---|---|---|---|---|
|
| ||||||||
| Outcome | LS Mean | SE | LS Mean | SE | LS Mean | SE | LS Mean | SE |
|
|
||||||||
| Average severity of fatigue over weeks 5–12 | 3.70 | 0.19 | 3.66 | 0.26 | 3.64 | 0.29 | 3.55 | 0.22 |
| Severity of fatigue at week 8 | 2.52 | 0.29 | 2.98 | 0.42 | 3.05 | 0.53 | 3.07 | 0.37 |
| Severity of fatigue at week 12 | 3.95 | 0.31 | 3.90 | 0.27 | 3.74 | 0.37 | 3.53 | 0.31 |
| Average severity index of other symptoms over weeks 5–12 | 27.50 | 1.16 | 28.78 | 2.40 | 28.58 | 2.49 | 26.69 | 1.61 |
| Summed severity index of other symptoms at week 8 | 18.12 | 2.51 1 | 25.15 | 3.371 | 19.02 | 2.24 | 22.20 | 2.43 |
| Summed severity index of other symptoms at week 12 | 30.43 | 2.41 | 28.30 | 2.92 | 30.52 | 2.88 | 29.50 | 1.96 |
| PROMIS anxiety at week 12 | 52.64 | 0.97 | 51.68 | 0.83 | 52.11 | 1.20 | 51.02 | 0.80 |
| PROMIS depression at week 12 | 51.16 | 0.56 | 50.42 | 0.88 | 51.60 | 1.12 | 51.07 | 0.85 |
1
Significant difference (p = .04) between two dynamic treatment regimens: (R, R) and (R, MP).
Note. LS = least square; SE = standard error; PROMIS = Patient Reported Outcomes Measurement Information System.