Fig. 6.

Syndromic profiles of cognitive and affective responses to laughter. The figure summarises the cognitive (laughter identification, ID) and affective (valence rating, face icon) responses to laughter subtypes (M, mirthful; H, hostile; P, posed; I, spectrally inverted) in the four dementia syndromes studied here. Shaded cells indicate a significantly abnormal alteration of laughter processing, coded as follows: white, no impairment; light grey, relative to healthy controls; dark grey, relative to the other disease group (FTD vs AD); black, relative to other syndromes within the FTD spectrum (see text and Supplementary Tables S1 and S4 for details). AD, patient group with typical Alzheimer's disease; bvFTD, patient group with behavioural variant frontotemporal dementia; nfvPPA, patient group with nonfluent-agrammatic variant primary progressive aphasia; svPPA, patient group with semantic variant primary progressive aphasia.