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. 2021 Aug 31;12:705543. doi: 10.3389/fimmu.2021.705543

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Copyright © 2021 Graversen, Larsen, Pedersen, Sørensen, Christoffersen, Jacobsen, Halken, Licht, Bahl and Bøgh

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effect of amoxicillin on the preventive capacity of the whey products. Ear swelling after intradermal injection of intact whey product on Day 63 in water (H₂O, open symbols) and amoxicillin (AMX, closed symbols) in rats administered with extensively (eHW), partially hydrolysed (pHW-22.4% and pHW-7.2%) or intact (iW) whey products or water as control (A). β-lactoglobulin (BLG) concentration in small intestine epithelium (EPI) and lamina propria (LP) after oral challenge with iW protein (B), iW-specific IgE titres (C), and iW-specific IgG1 titres (D). Subfigures (B–D) only show results for the eHW group. Each symbol represents a single rat and horizontal lines indicate mean (A) or median (B–D) values. Statistically significant differences are indicated as ***p ≤ 0.001.