Table 1.
Baseline characteristics of the study population.
| Endometriosis (n = 117) | Control (n = 200) | P-value | |
|---|---|---|---|
| Age (years) | 34.0 (32.0, 37.0) | 34.0 (31.0, 38.0) | 0.912 |
| BMI (kg/m2) | 20.6 (19.1, 22.3) | 21.6 (19.5, 23.4) | 0.022* |
| E2 (pg/mL) | 38.6 (30.7, 53.2) | 32.2 (23.9, 46.2) | 0.004** |
| P (ng/mL) | 0.4 (0.2, 0.5) | 0.4 (0.3, 0.6) | 0.084 |
| FSH (IU/L) | 7.3 (5.8, 8.5) | 6.9 (5.7, 8.3) | 0.430 |
| LH (IU/L) | 4.2 (3.1, 5.5) | 4.7 (3.7, 6.6) | 0.001** |
| PRL (ng/mL) | 14.8 (12.2, 18.5) | 16.2 (11.3, 21.0) | 0.276 |
| T (ng/mL) | 0.2 (0.2, 0.3) | 0.2 (0.1, 0.3) | 0.982 |
| Endometrial preparation program | 0.685 | ||
| Natural cycle | 57.3% (67/117) | 59.0% (118/200) | |
| Hormone replacement therapy cycle | 42.7% (50/117) | 41.0% (82/200) | |
| The percentage of RIF/RM/Others | <0.001*** | ||
| RIF | 35.9% (42/117) | 16.5% (33/200) | |
| RM | 17.9% (21/117) | 46.0% (92/200) | |
| Others | 46.2% (54/117) | 37.5% (75/200) | |
| Duration of post-operative period (years) | 3.0 (1.9, 5.5) | / |
BMI, body mass index; E2, estradiol; P, progesterone; FSH, follicle-stimulating hormone; LH, luteinizing hormone; PRL, prolactin; T, testosterone; RIF, repeated implantation failure; RM, recurrent miscarriage; Others, reproductive failure patients who failed to achieve a pregnancy or experienced miscarriage but not meeting the standard of RIF or RM.
Serum hormone levels were all detected on day 3 of the menstrual cycle.
Continuous variables without normal distribution: Mann–Whitney U test, and shown as median (interquartile range); categorical variables: Chi-square test, shown as percentages of participants.
The percentage of RIF: P = 0.002; the percentage of RM: P < 0.001.
*P < 0.05; *P < 0.01; ***P < 0.001.