Table 2.
Comparison of lymphocyte subsets from endometrium or peripheral blood and cytotoxicity of peripheral NK cells between females with or without a history of endometriosis.
| Endometriosis (n = 117) | Control (n = 200) | P-value | |
|---|---|---|---|
| eCD56+ (%) | 11.7 (7.9, 19.3) | 12.1 (8.5, 19.1) | 0.607 |
| eCD68+ (%) | 2.3 (1.6, 3.0) | 2.1 (1.5, 2.7) | 0.167 |
| eCD1a+ (%) | 0.06 (0.04, 0.10) | 0.05 (0.03, 0.10) | 0.183 |
| eCD83+ (%) | 1.8 (1.3, 2.4) | 1.7 (1.2, 2.5) | 0.760 |
| eCD57+ (%) | 0.4 (0.2, 0.5) | 0.3 (0.2, 0.5) | 0.558 |
| eCD8+ (%) | 2.9 (2.1, 4.0) | 3.0 (1.9, 4.2) | 0.684 |
| eFoxP3+ (%) | 0.10 (0.06, 0.14) | 0.09 (0.06, 0.13) | 0.512 |
| pCD3+ (%) | 69.4 ± 6.9 | 68.4 ± 8.2 | 0.288 |
| pCD3+CD8+ (%) | 26.1 (22.5, 30.8) | 25.6 (22.5, 29.8) | 0.931 |
| pCD3+CD4+ (%) | 37.1 ± 6.4 | 35.8 ± 6.7 | 0.094 |
| pCD56+CD16+ (%) | 15.3 (11.6, 20.3) | 16.9 (11.1, 21.7) | 0.564 |
| pCD19+ (%) | 12.1 (9.9, 15.7) | 12.7 (10.5, 15.1) | 0.775 |
| Cytotoxicity at ET25 (%) | 26.6 ± 14.5 | 33.3 ± 14.5 | <0.001*** |
| Cytotoxicity at ET50 (%) | 36.1 ± 15.6 | 43.3 ± 15.2 | <0.001*** |
e, endometrial cell; p, peripheral blood mononuclear cell.
Cytotoxicity, cytotoxicity of peripheral NK cells, shown as the ratios of target cell lysis. ET, the ratios between effectors and target cells.
Continuous variables with normal distribution: t-test, and shown as mean ± standard deviation; Continuous variables without normal distribution: Mann–Whitney U test, and shown as median (interquartile range).
***P < 0.001.