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. 2021 Aug 31;11:661288. doi: 10.3389/fonc.2021.661288

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Copyright © 2021 Gao, Li, Liu, Zhang, Gao and Wang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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MIR4435-2HG bind to miR-138-5p. (A) Specific binding sites of MIR4435-2HG with miR-138-5p. (B) qRT-PCR detection of miR-138-5p in gastric carcinoma patients. (C) Pearson’s test analyzed the correlation of MIR4435-2HG with miR-138-5p in gastric carcinoma patients. (D) RNA immunoprecipitation (RIP) experiment confirmed that MIR4435-2HG combined with miR-138-5p in SGC-7901 and MGC-803 cells. (E) Double luciferase report confirmed that MIR4435-2HG combined with miR-138-5p in SGC-7901 and MGC-803 cells. (F) MiR-138-5p in gastric carcinoma cells transfected with si-MIR4435-2HG#1 was tested using qRT-PCR in SGC-7901 and MGC-803 cells. * indicates p < 0.05; ** indicates p < 0.01; *** indicates p < 0.001.