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. 2021 Aug 31;11:661288. doi: 10.3389/fonc.2021.661288

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Copyright © 2021 Gao, Li, Liu, Zhang, Gao and Wang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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miR-138-5p targeted Sox4. (A) Specific binding sites of miR-138-5p and Sox4. (B) qRT-PCR was applied to test Sox4 in gastric carcinoma patients. (C) Pearson’s test was applied to test the correlation of Sox4 with MIR4435-2HG and miR-138-5p. (D) Double luciferase report confirmed that MIR4435-2HG combined with miR-138-5p in SGC-7901 and MGC-803 cells. (E, F) qRT-PCR and Western blotting (WB) were applied to test miR-138-5p in gastric carcinoma cells transfected with si-MIR4435-2HG#1 in SGC-7901 and MGC-803 cells. * indicates p < 0.05; *** indicates p < 0.001.