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. 2021 Aug 31;11:661653. doi: 10.3389/fonc.2021.661653

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Copyright © 2021 Chen, Zhang and Wang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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miR-9-5p has a targeted regulation relationship with ABCC1. (A) miR-9-5p and ABCC1 target binding site. (B) qRT-PCR was used to detect the relative expression of ABCC1 in tumor tissues of patients with glioma. (C) Correlation analysis showed that miR-9-5p was negatively correlated with ABCC1. (D) Double luciferase report analysis of miR-9-5p and ABCC1 targeted binding. (E) qRT-PCR and WB test were used to detect the relative expression of ABCC1 in U87-TMZ/U251-TMZ cells after up-regulating miR-9-5p. *indicates P < 0.05; *** indicates P < 0.001.