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. 2021 Aug 31;11:661653. doi: 10.3389/fonc.2021.661653

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Copyright © 2021 Chen, Zhang and Wang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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miR-9-5p can reverse the sensitization of ABCC1 to glioma TMZ. (A) qRT-PCR was used to detect the relative expression of ABCC1 in U87-TMZ/U251-TMZ cells after co-transfection. (B, C) The activity and IC50 of U87-TMZ/U251-TMZ cells were detected by MTT assay. (D) The change of apoptosis rate of U87-TMZ/U251-TMZ cells after co-transfection was detected by flow cytometry. * indicates P < 0.05; ** indicates P < 0.01.