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. 2021 Aug 31;12:679415. doi: 10.3389/fneur.2021.679415

Table 1.

Clinical characteristics between groups with/without aICAS.

Variable Without aICAS With aICAS P-value
N (%) 4,619 (86.9) 695 (13.1)
Age, years 51.72 (45.36–59.91) 59.00 (49.91–72.48) <0.001
Male, n (%) 2,750 (59.5) 443 (63.7) 0.035
High school or above, n (%) 2,046 (44.3) 262 (31.7) 0.001
Income >1,000 RMB/m, n (%) 3,617 (78.3) 561 (80.7) 0.148
BMI, kg/m2 24.72 (22.65–26.99) 24.77 (22.86–27.34) 0.355
Systolic blood pressure, mm Hg 130.0 (118.7–140.0) 140.0 (130.0–156.7) <0.001
Diastolic blood pressure, mm Hg 80.67 (76.67–90.00) 80.67 (76.67–90.00) 0.061
Current smoker, n (%) 1,481 (32.1) 220 (32.0) 0.830
Current alcohol use, n (%) 672 (14.6) 82 (11.8) 0.053
Active physical activity, n (%) 2,753 (59.6) 2,753 (59.6) 0.226
Diabetes, n (%) 484 (10.5) 149 (21.4) <0.001
Hypertension, n (%) 2,065 (44.7) 475 (60.4) <0.001
Dyslipidemia, n (%) 2,176 (47.1) 372 (53.5) 0.002
Antihypertensive agents, n (%) 752 (16.3) 256 (36.8) <0.001
Antidiabetic agents, n (%) 227 (4.9) 85 (12.2) <0.001
FBG, mmol/L 5.20 (4.81–5.72) 5.40 (4.89–6.22) <0.001
TC, mmol/L 4.91 (4.33–5.59) 5.17 (4.51–5.81) <0.001
TG, mmol/L 1.29 (0.92–1.92) 1.32 (0.98–1.92) 0.167
HDL-C, mmol/L 1.57 (1.31–1.90) 1.32 (0.98–1.85) 0.051
LDL-C, mmol/L 2.59 (2.16–3.04) 2.70 (2.21–3.15) 0.002
Non-HDL-C, mmol/L 3.29 (2.74–3.97) 3.63 (2.96–4.25) <0.001
TG/HDL-C 0.83 (0.54–1.31) 0.88 (0.58–1.34) 0.054
AC 2.09 (1.60–2.78) 2.37 (1.76–3.04) <0.001
AIP −0.19 (−0.61–0.27) −0.13 (−0.54–0.29) 0.054
CRI-I 3.09 (2.60–3.97) 3.37 (2.76–4.04) <0.001
CRI-II 1.63 (1.28–2.04) 1.73 (1.35–2.19) <0.001