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. 2021 Aug 31;12:670389. doi: 10.3389/fphar.2021.670389

FIGURE 3.

FIGURE 3

Effects of sitagliptin on the pathological changes in the thoracic aorta from the HFD-fed rats. Pathological changes in the thoracic aorta were evaluated with HE staining; Oil-red O staining; Masson trichrome staining; immunohistochemical staining of CD68 and TUNEL staining respectively. Representative photographs were displayed here. scale bars = 50 μm (×400). SCD: standard chow diet; HFD: high-fat diet; HFD + SIT: HFD and SIT therapy group. Typical changes are marked with black arrows in the images of HE, CD68 and TUNEL staining. Quantification of CD68 and TUNEL staining were also shown, values displayed are mean ± SEM from three representative images.**p < 0.01,***p < 0001 vs. SCD group; # p < 0.05,## p < 0.01 vs. HFD group.