TABLE 2.
Metabolic characteristics of WT and fat-1 mice in an acute-on-chronic model of ALD.
| Characteristic | WT Pair-Fed | Fat-1 Pair-Fed | WT EtOH | Fat-1 EtOH |
|---|---|---|---|---|
| Food Consumption (g per day per mouse) | * | * | 10.18 ± 0.64 | 9.19 ± 0.49 |
| Weights | ||||
| Initial BW (g) | 27.32 ± 0.86 | 26.83 ± 0.68 | 27.75 ± 0.43 | 27.39 ± 0.61 |
| Final BW (g) | 27.80 ± 0.84 | 26.67 ± 0.63 | 26.54 ± 0.37 | 26.80 ± 0.55 |
| Body Weight Gain (%) | 1.76 ± 0.04 | −0.60 ± 0.03 | −4.63 ± 0.02 | −2.15 ± 0.03 |
| Liver/BW Ratio (%) | 3.50 ± 0.28 | 3.95 ± 0.14 | 4.00 ± 0.08 | 4.17 ± 0.11 |
| Fat/BW Ratio (%) | 0.14 ± 0.02 | 0.09 ± 0.01 | 0.12 ± 0.01 | 0.10 ± 0.01 |
| Blood alcohol concentration (mM) | 1.849 ± 0.20 | 2.001 ± 0.08 | 49.34 ± 17.45 | 40.52 ± 13.51 |
* PF mice consume the same amount of food as EtOH-fed mice, per genotype.