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. 2021 Sep 9;9(1):e002263. doi: 10.1136/bmjdrc-2021-002263

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© Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution 4.0 Unported (CC BY 4.0) license, which permits others to copy, redistribute, remix, transform and build upon this work for any purpose, provided the original work is properly cited, a link to the licence is given, and indication of whether changes were made. See: https://creativecommons.org/licenses/by/4.0/.

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Time-to-diagnosis behavior of the most significantly altered initial glycan traits in individuals who developed insulin resistance/type 2 diabetes from the TwinsUK cohort. Glycan abundance is presented on the y axis with dots representing calculated means and lines representing 95% CI, while different temporal groups are presented on the x axis. The timepoint period in which the disease diagnosis occurred is labeled brown, while all prediagnosis timepoint periods are labeled blue. Numbers listed inside the brackets represent years of distance from diagnosis. GP, glycan peak.