Table 1.
Demographic characteristics and baseline biochemical and hematological indices.
| <35 | 35–65 | >65 | Total | p value | |
|---|---|---|---|---|---|
| N | 93 | 89 | 93 | 275 | |
| Age (years) | 27.17 (4.53) | 52.30 (9.19) | 75.40 (6.78) | 51.61 (21.08) | <0.0011 |
| Sex | <0.0012 | ||||
| F | 57 (61.29%) | 38 (42.70%) | 25 (26.88%) | 120 (43.64%) | |
| M | 36 (38.71%) | 51 (57.30%) | 68 (73.12%) | 155 (56.36%) | |
| Aβ1–42 (pg/ml) | 14.76 (4.16) | 19.96 (5.96) | 18.67 (6.36) | 17.76 (5.97) | <0.0013 |
| AST (U/L) | 23.41 (9.46) | 25.82 (8.73) | 23.46 (12.56) | 24.21 (10.43) | 0.0021 |
| ALT (U/L) | 24.89 (6.09) | 26.03 (9.09) | 22.44 (13.61) | 24.43 (10.17) | <0.0011 |
| GGT (U/L) | 25.49 (8.20) | 26.17 (11.88) | 22.30 (23.65) | 24.63 (16.08) | <0.0011 |
| Bilirubin (μmol/L) | 0.76 (0.43) | 0.75 (0.34) | 0.64 (0.31) | 0.72 (0.37) | 0.0471 |
| Cholesterol (mmol/L) | 179.06 (26.53) | 180.56 (29.59) | 179.20 (35.86) | 179.60 (30.82) | 0.9374 |
| HDL (mmol/L) | 49.51 (10.49) | 42.88 (10.16) | 48.41 (13.11) | 46.99 (11.67) | <0.0011 |
| Triglycerides (mmol/L) | 110.97 (45.86) | 108.46 (33.32) | 97.96 (50.95) | 105.78 (44.32) | 0.0051 |
| Creatinine (μmol/L) | 0.69 (0.26) | 0.70 (0.24) | 0.96 (0.32) | 0.79 (0.30) | <0.0011 |
| Glucose (mmol/L) | 81.62 (10.94) | 85.34 (15.62) | 101.38 (20.89) | 89.51 (18.43) | <0.0011 |
| Total Protein (g/L) | 7.29 (0.52) | 7.31 (0.58) | 6.88 (0.48) | 7.16 (0.56) | <0.0011 |
| TSH (mIU/L) | 1.58 (0.73) | 1.38 (0.66) | 1.72 (0.95) | 1.56 (0.80) | |
| Urea (mmol/L) | 27.80 (6.41) | 28.00 (9.67) | 42.18 (10.66) | 32.73 (11.31) | <0.0011 |
| WBC (10E9/L) | 6.45 (1.66) | 6.21 (1.54) | 5.82 (1.54) | 6.16 (1.60) | |
| Erythrocytes (10E12/L) | 4.89 (0.55) | 4.85 (0.56) | 4.85 (0.56) | 4.86 (0.56) | 0.8981 |
| Platelets (10E9/L) | 242.14 (54.80) | 244.35 (58.75) | 205.81 (49.05) | 230.57 (56.92) | <0.0011 |
| Hb (g/L) | 13.58 (1.53) | 13.69 (1.55) | 13.78 (1.61) | 13.68 (1.56) | 0.6744 |
AST, aspartate aminotransferase; ALT, alanine aminotransferase; GGT, gamma glutamyl transpeptidase; HDL-cholesterol, high-density lipoprotein cholesterol; TSH, thyroid-stimulating hormone; WBC, white blood cells; Hb, hemoglobin. The results are reported as mean ± standard deviation (SD) Comparisons by age groups. 1Kruskal-Wallis rank sum test. 2Pearson’s Chi-squared test. 3One-way analysis of means (not assuming equal variances). 4Linear Model ANOVA.