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. 2021 Aug 31;13:698571. doi: 10.3389/fnagi.2021.698571

Table 2.

Correlations between Aβ1–42 measurements and clinical parameters observed in this study.

Variable Overall 1st Group 2nd Group 3rd Group
1–42/rs p-value adj.p 1–42/rs p-value adj.p 1–42/rs p-value adj.p 1–42/rs p-value adj.p
Sex M 17.89 ± 6.45 0.67 14.55 ± 5.00 0.71 21.09 ± 6.06 0.20 18.85 ± 6.88 0.94
F 17.59 ± 5.31 14.89 ± 3.57 18.95 ± 5.76 18.31 ± 4.77
Age 0.27 <0.0001 <0.0001 −0.25 0.01 0.56 0.22 0.03 0.52 0.02 0.86 0.95
ALT −0.06 0.31 0.66 0.03 0.76 0.78 0.08 0.47 0.98 −0.17 0.09 0.58
AST −0.04 0.48 0.50 −0.16 0.12 0.97 −0.01 0.93 0.87 −0.12 0.25 0.37
GGT −0.01 0.86 0.91 −0.01 0.94 0.99 0.2 0.06 0.56 0.02 0.85 0.95
Bilirubin −0.01 0.84 0.90 0.07 0.51 0.96 −0.05 0.65 0.95 −0.06 0.55 0.82
Cholesterol 0.12 0.04 0.13 −0.06 0.56 0.97 0.2 0.06 0.56 0.18 0.08 0.34
HDL −0.06 0.31 0.41 0.12 0.25 0.97 −0.05 0.62 0.95 0.06 0.56 0.26
Triglycerides 0.07 0.22 0.50 −0.04 0.67 0.93 0.03 0.80 0.95 0.21 0.04 0.82
Creatinine 0.08 0.17 0.35 0.02 0.82 0.97 −0.07 0.49 0.87 0.13 0.22 0.55
Glucose 0.09 0.14 0.37 −0.11 0.27 0.93 −0.02 0.88 0.98 0.08 0.46 0.78
Total proteins −0.11 0.05 0.16 0.1 0.36 0.93 −0.15 0.15 0.78 −0.2 0.05 0.29
TSH 0.06 0.37 0.50 −0.09 0.38 0.93 0.1 0.37 0.87 0.22 0.04 0.24
Urea 0.09 0.13 0.31 −0.01 0.93 0.99 0.04 0.74 0.95 0.03 0.8 0.95
RBC −0.06 0.28 0.34 −0.13 0.22 0.97 0.09 0.42 0.99 −0.14 0.18 0.51
WBC −0.09 0.15 0.48 0.05 0.67 0.93 0 0.99 0.87 −0.15 0.16 0.53
Platelets −0.04 0.56 0.71 −0.1 0.34 0.93 0.08 0.44 0.87 −0.01 0.93 0.99
Hb 0.02 0.70 0.83 −0.03 0.78 0.97 0.04 0.74 0.95 0.01 0.93 0.99

P-values refer to the Spearman correlation test (adj.p for Benjamini-Hochberg procedure for multiple testing) for continuous variables and to the t-test (Welch test for unequal variances for the overall groups) for categorical variable. Bold values denote statistical significance at the p ≤ 0.05 level.