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. 2021 Sep 13;8(2):e001735. doi: 10.1136/openhrt-2021-001735

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© Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution 4.0 Unported (CC BY 4.0) license, which permits others to copy, redistribute, remix, transform and build upon this work for any purpose, provided the original work is properly cited, a link to the licence is given, and indication of whether changes were made. See: https://creativecommons.org/licenses/by/4.0/.

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Relationships between traditional risk factors and incident atrial fibrillation. Left is results from the ULSAM longitudinal study with 40 years follow-up and right is results from two-sample Mendelian randomisation (MR). Results are given both for a univariate (risk factors analysed one by one) and a multivariate model (including all risk factors in the same model). BMI, body mass index; HDL, high-density lipoprotein; LDL, low-density lipoprotein; SBP, systolic blood pressure; ULSAM, Uppsala Longitudinal Study of Adult Men.