Table 2.
In vitro antifungal susceptibility profile of Aspergillus species isolated (n = 117) against triazole antifungal agents.
| Species (number of isolates) | Drug | MIC (mg/l) | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Range | 0.015 | 0.03 | 0.06 | 0.125 | 0.25 | 0.5 | 1.0 | 2.0 | ||
| Aspergillus niger (50) | ITC | 2 | – | – | – | – | – | – | – | 50 |
| VRZ | 1–2 | – | – | – | – | – | – | 12 | 38 | |
| Aspergillus flavus (37) | ITC | 0.06–0.50 | – | – | 10 | 5 | 10 | 12 | – | – |
| VRZ | 0.25–0.50 | – | – | – | – | 12 | 15 | – | – | |
| Aspergillus terreus (20) | ITC | 0.5 | – | – | – | – | – | 20 | – | – |
| VRZ | 0.5 | – | – | – | – | – | 20 | – | – | |
| Aspergillus fumigatus (5) | ITC | 0.06–0.25 | – | – | 2 | 2 | 1 | – | – | – |
| VRZ | 0.015–0.250 | 1 | 2 | – | 1 | 1 | – | – | – | |
| Aspergillus nidulans (5) | ITC | 0.125–0.500 | – | – | – | 3 | – | 2 | – | – |
| VRZ | 0.125–0.500 | – | – | – | 2 | 2 | 1 | – | – | |
ITC, itraconazole; MIC, Minimum Inhibitory Concentration; VRZ, voriconazole.