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. 2021 Sep 13;22:658. doi: 10.1186/s12864-021-07940-4

Table 3.

Top 20 genes with highest degree in network

Gene Function Betweenness Degree Indegreea Outdegreeb ModuleID
cyp1a cytochrome P450, family 1, subfamily A 0.00235481 41 17 24 13
sult6b1 sulfotransferase family, cytosolic, 6b, member 1 0.01272304 41 12 29 13
cyp1c1 cytochrome P450, family 1, subfamily C, polypeptide 1 0.00466897 39 17 22 13
cyp1c2 cytochrome P450, family 1, subfamily C, polypeptide 2 0.00712917 37 19 18 13
gng13b guanine nucleotide binding protein (G protein), gamma 13b 0.03415074 37 12 25 4
gstp1 glutathione S-transferase pi 1 0.06511838 34 14 20 13
wfikkn1 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1 0.00465263 34 16 18 13
ahrra aryl-hydrocarbon receptor repressor a 0.0040985 33 17 16 13
foxq1a forkhead box Q1a 0.00479027 33 13 20 13
mxd1 MAX dimerization protein 1 0.03254926 32 9 23 2
slincR None 8.00E-04 32 15 17 13
zgc.158689 None 0.01270125 31 13 18 2
cacna1da calcium channel, voltage-dependent, L type, alpha 1D subunit, a 0.10295178 30 5 25 2
osbpl2a oxysterol binding protein-like 2a 0.01197251 30 8 22 2
srgap3 SLIT-ROBO Rho GTPase activating protein 3 0.01114073 30 10 20 2
tfe3a transcription factor binding to IGHM enhancer 3a 0.07136245 30 11 19 2
cyb5a cytochrome b5 type A (microsomal) 0.00566261 28 15 13 13
pkhd1l1 polycystic kidney and hepatic disease 1 (autosomal recessive)-like 1 0.04172331 28 12 16 13
NA_732 None 7.84E-04 27 13 14 13
NA_146 None 0.01266327 26 5 21 2

a Number of edges emanating to the gene

b Number of edges emanating from the gene