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Number of patients in each category of CIBIC-Plus
| Baseline | Week 4 | Week 8 | Week 12 | |||||
|---|---|---|---|---|---|---|---|---|
| Low dose | High dose | Low dose | High dose | Low dose | High dose | Low dose | High dose | |
| Marked worsening | ||||||||
| Moderate worsening | 1 | 1 | 3 | |||||
| Minimal worsening | 2 | 2 | 1 | |||||
| No change | 3 | 3 | 2 | 2 | 2 | 1 | ||
| Minimal improvement | 1 | 1 | 1 | 2 | 2 | 1 | 1 | |
| Moderate improvement | 1 | 1 | 1 | |||||
| Marked improvement | 1 | |||||||
CIBIC-Plus, Clinician’s Interview-Based Impression of Change Plus Caregiver Input
