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. 2021 Sep 14;12:502. doi: 10.1186/s13287-021-02453-z

Table 1.

Demographic and disease characteristics of donors

Characteristics C-SF-MSCs
(n = 10)
E-RA-SF-MSCs
(n = 9)
L-RA-SF-MSCs
(n = 12)
P value*
Age (years) 23.0 (1.22) 55.4 (14.1) 58.5 (8.6) -
Women 3 (30%) 8 (88.8%) 12 (100%) -
Positive for rheumatoid factor - 8 (88.8%) 12 (100%) -
Positive for anti-CCP antibody - 8 (88.8%) 12 (100%) -
DAS28-ESR - 5.1 (1.4) 4.6 (1.1) -
Disease duration (years) - 1.7 (1.1) 13.8 (5.1) 0.011
Modified Sharp score - 7.9 (8.8) 49.7 (26.4) 0.015

Data are means (SE) or n (%), *P value indicates E-SF-MSC vs. L-SF-MSC. C-SF control synovial fluid, ERA or LRA early or long-standing rheumatoid arthritis, MSC mesenchymal stem cell, CCP cyclic citrullinated peptide, DAS28-ESR disease activity score 28-erythrocyte sediment rate