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. 2021 Sep 14;22:53. doi: 10.1186/s12868-021-00658-9

Table 1.

The cellular uptake of Aβ1-42 in GFP-HEK293T cells and OATP1B1-GFP-HEK293T cells following incubation with 0.4, 1, 2.5 μM Aβ1-42 for 24, 48, 72 h, respectively (n = 3)

1-42 0 μM 1-42 0.4 μM 1-421 μM 1-42 2.5 μM
NC OATP1B1 NC OATP1B1 NC OATP1B1 NC OATP1B1
24 h 0.52 ± 0.05 0.47 ± 0.12 9.16 ± 0.93 10.88 ± 0.31* 16.28 ± 2.42 24.50 ± 4.48* 36.01 ± 4.25 42.00 ± 4.27
48 h 0.62 ± 0.11 0.67 ± 0.15 12.18 ± 0.25 19.87 ± 1.70** 20.07 ± 0.98 49.42 ± 3.02** 37.04 ± 1.77 65.38 ± 4.52**
72 h 0.52 ± 0.07 0.63 ± 0.10 16.92 ± 0.20 29.53 ± 2.58** 24.61 ± 4.57 56.60 ± 8.03** 44.39 ± 5.76 84.13 ± 3.03**

NC GFP-HEK293T cells; OATP1B1 OATP1B1-GFP-HEK293T cells

*P < 0.05; **P < 0.01