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. 2021 Sep 14;15(1):51. doi: 10.1186/s13065-021-00777-8

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 4 — The scatterplot shows how all adducted and control sequences correlate with the first dimension (Dim1) and the second dimension (Dim2). Those is grey are controls and those in colour with a * are adducted sequences. In A and B K12C donates the altered K12 sequence containing a C in place of a T and in B K12MethC denotes the altered sequence containing a Methylated C in place of a T. The sequences of K12 are displayed above the charts with diagrammatic indicators of adducted sites