Table 1. Biologics for the treatment of atopic dermatitis in clinical trials.
| Agent | Mechanism | Trial Phase |
|---|---|---|
| Lebrikizumab | Anti-IL-13 mAb | Phase 3 |
| Nemolizumab | Anti-IL-31RA mAb | Phase 3 |
| GBR830 | Anti-OX40 mAb | Phase 2 |
| KY1005 | Anti-OX40 mAb | Phase 2 |
| Tezepelumab | Anti-TSLP mAb | Phase 2 |
| ANB020/Etokimab | Anti-IL-33 mAb | Phase 2, early terminated |
| PF-06817024 | Anti-IL-33 mAb | Phase 1 |
| Fezakinumab | Anti-IL-22 mAb | Phase 2 |
| Bermekimab | Anti-IL-1α mAb | Phase 2 |