Table 2.
Characteristics of patients with sepsis.
| All patients (n=294) | Non-septic shock | Septic shock | |||||
|---|---|---|---|---|---|---|---|
| Survival (n=74) | Death (n=80) | P | Survival (n=51) | Death (n=89) | P | ||
| Age, years, median (Q1, Q3) | 67 (55–76) | 66 (51–74) | 70 (56–78) | 0.067 | 62 (53–74) | 67 (58–79) | 0.087 |
| Male, n (%) | 185 (62.9) | 43 (58.1) | 57 (71.3) | 0.088 | 28 (54.9) | 57 (64.0) | 0.286 |
| Household registration | 0.063 | 0.849 | |||||
| Countryside | 180 (61.2) | 48 (64.9) | 40 (50.0) | 33 (64.7) | 59 (66.3) | ||
| Urban | 114 (38.8) | 26 (35.1) | 40 (50.0) | 18 (35.3) | 30 (33.7) | ||
| Patient sources | 0.008 | <0.001 | |||||
| Emergency treatment | 69 (23.5) | 11 (14.9) | 22 (27.5) | 5 (9.8) | 31 (34.8) | ||
| Postoperative transfer | 55 (18.7) | 19 (25.7) | 6 (7.5) | 20 (39.2) | 10 (11.2) | ||
| General wards (including general wards and their ICU) | 151 (51.4) | 36 (48.6) | 46 (57.5) | 26 (51.0) | 43 (48.3) | ||
| Specialty or ICU from other hospitals | 19 (6.5) | 8 (10.8) | 6 (7.5) | 0 (0) | 5 (5.6) | ||
| Major diseases to ICU | 0.246 | 0.032 | |||||
| Respiratory diseases | 113 (38.4) | 29 (39.2) | 44 (55.0) | 10 (19.6) | 30 (33.7) | ||
| Circulatory diseases | 10 (3.4) | 2 (2.7) | 2 (2.5) | 0 (0) | 6 (6.7) | ||
| Diseases of digestive system | 92 (31.3) | 23 (32.1) | 12 (15.0) | 26 (51.0) | 31 (34.8) | ||
| Neurological diseases | 25 (8.5) | 4 (5.4) | 9 (11.3) | 3 (5.9) | 9 (10.1) | ||
| Endocrine system diseases | 5 (1.7) | 1 (1.4) | 2 (2.5) | 0 (0) | 2 (2.2) | ||
| Diseases of urinary system | 22 (7.5) | 6 (8.1) | 4 (5.0) | 8 (15.7) | 4 (4.5) | ||
| Hematological diseases | 4 (1.4) | 1 (1.4) | 1 (1.3) | 0 (0) | 2 (2.2) | ||
| Rheumatic immune system diseases | 1 (0.3) | 0 (0) | 1 (1.3) | ||||
| Trauma | 10 (3.4) | 3 (4.1) | 3 (3.8) | 2 (3.9) | 2 (2.2) | ||
| Other | 12 (4.1) | 5 (6.8) | 2 (2.5) | 2 (3.9) | 3 (3.4) | ||
| Underlying diseases | |||||||
| None | 90 (30.6) | 27 (36.5) | 20 (25.0) | 0.122 | 21 (41.2) | 22 (24.7) | 0.042 |
| Coronary heart disease | 45 (15.3) | 6 (8.1) | 17 (21.3) | 0.022 | 5 (9.8) | 17 (19.1) | 0.146 |
| Diabetes | 60 (20.4) | 18 (24.3) | 19 (25.6) | 0.934 | 6 (11.8) | 17 (19.1) | 0.260 |
| Malignant tumors | 22 (7.5) | 4 (5.4) | 5 (6.3) | 1.000 | 3 (5.9) | 10 (11.2) | 0.455 |
| Autoimmune diseases | 11 (3.7) | 2 (27) | 7 (8.8) | 0.210 | 2 (3.9) | 0 (0) | 0.131 |
| Chronic renal insufficiency and failure | 18 (6.1) | 6 (8.1) | 7 (8.8) | 0.886 | 1 (2.0) | 4 (4.5) | 0.761 |
| Hypertension | 95 (32.3) | 22 (29.7) | 35 (43.8) | 0.072 | 8 (15.7) | 30 (33.7) | 0.021 |
| Chronic obstructive pulmonary disease | 34 (11.6) | 10 (13.5) | 11 (13.8) | 0.966 | 2 (3.9) | 11 (12.4) | 0.176 |
| Sequelae of cerebrovascular accident | 18 (6.1) | 3 (4.1) | 8 (10.0) | 0.152 | 3 (5.9) | 4 (4.5) | 1.000 |
| Other | 65 (22.1) | 14 (18.9) | 16 (20.0) | 0.866 | 11 (21.6) | 24 (27.0) | 0.478 |
| Chronic organ dysfunction | |||||||
| Chronic cardiac insufficiency | 22 (7.5) | 4 (5.4) | 7 (8.8) | 0.421 | 1 (2.0) | 10 (11.2) | 0.102 |
| Chronic respiratory insufficiency | 41 (13.9) | 10 (13.5) | 16 (20.0) | 0.283 | 5 (9.8) | 10 (11.2) | 0.792 |
| Chronic hepatic insufficiency | 6 (2.0) | 0 (0.0) | 3 (3.8) | 0.272 | 0 (0) | 3 (3.4) | 0.472 |
| Immunosuppression | 17 (5.8) | 2 (2.7) | 7 (8.8) | 0.210 | 2 (3.9) | 6 (6.7) | 0.754 |
| Chronic renal insufficiency | 6 (2.0) | 3 (4.1) | 1 (1.3) | 0.558 | 1 (2.0) | 1 (1.1) | 1.000 |
| None | 210 (71.4) | 56 (75.7) | 52 (65.0) | 0.148 | 43 (84.3) | 59 (66.3) | 0.021 |
| Number of acute organ dysfunction | 0.016 | 0.182 | |||||
| 1 | 3 (1.0) | 1 (1.4) | 1 (1.3) | - | 1 (2.0) | 0 (0) | |
| 2 | 33 (11.3) | 19 (25.7) | 11 (13.8) | 0 (0) | 3 (3.4) | ||
| 3 | 63 (21.5) | 26 (35.1) | 18 (22.5) | 9 (17.6) | 10 (11.4) | ||
| ≥4 | 194 (66.2) | 28 (37.8) | 50 (62.5) | 41 (80.4) | 75 (85.2) | ||
| Acute organ dysfunction involvement system (scored by sequential organ failure score (SOFA)) | |||||||
| Respiratory system | 282 (96.2) | 67 (90.5) | 79 (98.8) | 0.054 | 49 (96.1) | 87 (98.9) | 0.629 |
| Coagulation system | 186 (63.5) | 47 (63.5) | 47 (58.8) | 0.545 | 38 (74.5) | 54 (61.4) | 0.114 |
| Liver | 116 (39.6) | 25 (33.8) | 31 (38.8) | 0.522 | 18 (35.3) | 42 (47.7) | 0.154 |
| Cardiovascular system | 200 (68.3) | 26 (35.1) | 41 (51.3) | 0.044 | 48 (94.1) | 85 (96.6) | 0.796 |
| Central nervous system | 236 (80.5) | 45 (60.8) | 69 (86.3) | 0.000 | 40 (78.4) | 82 (93.2) | 0.011 |
| Kidney | 170 (58.0) | 34 (45.9) | 39 (48.8) | 0.728 | 31 (60.8) | 66 (75.0) | 0.079 |
| Infection type | 0.719 | 0.647 | |||||
| Community infection | 247 (84) | 60 (81.1) | 63 (78.8) | 46 (90.2) | 78 (87.6) | ||
| Hospital acquired infections | 47 (16) | 14 (18.9) | 17 (21.2) | 5 (9.8) | 11 (12.4) | ||