Table 3.
Univariate and multivariate logistic regression analyses of risk factors for HT in AIS patients with MT.
| Univariate | Multivariate | |||
|---|---|---|---|---|
| Parameters | cOR (95% CI) | p -value | aOR (95% CI) | p -value |
| Sex (male vs. female) | 1.38 (0.67–2.80) | 0.381 | ||
| Age (age in years) | 1.76 (1.01–3.05) | 0.046 | ||
| Smoking | 0.50 (0.22–1.15) | 0.104 | ||
| Drinking | 0.73 (0.28–1.92) | 0.522 | ||
| Hypertension | 0.85 (0.41–1.74) | 0.650 | ||
| Diabetes mellitus | 0.79 (0.36–1.76) | 0.567 | ||
| History of stroke or TIA | 0.54 (0.18–1.58) | 0.260 | ||
| Coronary artery disease | 1.75 (0.68–4.47) | 0.244 | ||
| Atrial fibrillation | 1.19 (0.58–2.41) | 0.635 | ||
| Baseline SBP | 0.95 (0.61–1.48) | 0.811 | 0.86 (0.53–1.41) | 0.559 |
| Baseline DBP | 1.12 (0.70–1.77) | 0.637 | 1.11 (0.68–1.82) | 0.671 |
| Baseline NIHSS | 0.80 (0.51–1.26) | 0.337 | 0.81 (0.50–1.33) | 0.408 |
| Glucose | 0.78 (0.51–1.19) | 0.244 | 0.68 (0.40–1.17) | 0.163 |
| Leukocyte | 1.03 (0.61–1.75) | 0.910 | 1.14 (0.65–2.02) | 0.640 |
| Platelet | 0.54 (0.32–0.90) | 0.017 | 0.58 (0.33–0.99) | 0.048* |
| Hemoglobin | 1.15 (0.73–1.81) | 0.538 | 1.69 (0.92–3.11) | 0.094 |
| PT | 0.97 (0.86–1.09) | 0.570 | 0.94 (0.75–1.19) | 0.620 |
| APTT | 1.11 (0.93–1.34) | 0.251 | 1.10 (0.91–1.34) | 0.333 |
| INR | 1.08 (0.77–1.51) | 0.652 | 1.01 (0.71–1.44) | 0.946 |
| Fibrinogen | 0.49 (0.29–0.82) | 0.007 | 0.41 (0.23–0.72) | 0.002* |
| D-dimer | 1.05 (0.94–1.17) | 0.352 | 1.04 (0.96–1.13) | 0.285 |
| Creatinine | 1.02 (0.70–1.49) | 0.901 | 1.00 (0.66–1.51) | 0.997 |
| Urea | 1.16 (0.80–1.68) | 0.322 | 1.16 (0.80–1.68) | 0.431 |
| Uric acid | 0.83 (0.50–1.39) | 0.480 | 0.83 (0.48–1.45) | 0.516 |
| Potassium | 1.16 (0.72–1.86) | 0.552 | 1.18 (0.71–1.97) | 0.515 |
| Sodium | 1.13 (0.79–1.61) | 0.493 | 1.17 (0.81–1.70) | 0.407 |
| Chlorine | 0.85 (0.57–1.27) | 0.418 | 0.86 (0.56–1.32) | 0.494 |
| Troponin | 0.94 (0.83–1.07) | 0.361 | 0.90 (0.74–1.09) | 0.289 |
| BNP | 1.02 (0.72–1.45) | 0.908 | 0.73 (0.44–1.22) | 0.229 |
| Anticoagulant agent | 1.53 (0.67–3.54) | 0.315 | 1.45 (0.73–2.87) | 0.235 |
| Intravenous thrombolysis | 0.93 (0.45–1.93) | 0.850 | 1.52 (0.77, 2.98) | 0.704 |
| T1, h, median (IQR) | 0.92 (0.63, 1.34) | 0.676 | 0.90 (0.60, 1.35) | 0.614 |
| T2, h, median (IQR) | 0.91 (0.63, 1.3) | 0.596 | 0.89 (0.6, 1.32) | 0.550 |
| T2–T1, h, median (IQR) | 0.87 (0.52, 1.47) | 0.382 | 0.89 (0.51, 1.56) | 0.691 |
HT, hemorrhagic transformation; AIS, acute ischemic stroke; MT, mechanical thrombectomy; cOR, crude odds ratio; aOR, adjusted odds ratio; CI, confidence interval; TIA, transient ischemic attack; SBP, systolic blood pressure; DBP, diastolic blood pressure; NIHSS, National Institutes of Health Stroke Scale; PT, prothrombin time; APTT, activated partial thromboplastin time; INR, international normalized ratio; BNP, B-type natriuretic peptide; T1, time from symptom onset to puncture; T2, time from symptom onset to vascular recanalization; T2–T1, time of mechanical thrombectomy treatment.
Bold* values indicate p < 0.05.