Table 4: Comparison of changes in subjects treated using clear aligners and subjects treated using conventional fixed appliances ( Brackets ). Negative values indicate decreasing and positive values indicate increasing over time; difference was calculated using clear aligners minus conventional fixed appliances.

	Invisalign			Brackets			Invisalign vs. braces (diff.)
Variables	Mean	SD	Prob.	Mean	SD	Prob.	Mean	SE	Prob.
OB	-0.09	1.09	0.584	-1.15	1.61	0.003	-1.06	0.38	0.009
SN_MP	0.43	1.07	0.011	0.01	0.82	0.959	0.42	0.26	0.113
FMA	0.53	1.02	0.001	-0.00	0.79	0.979	0.53	0.25	0.038
L6H	0.17	0.61	0.068	0.63	0.76	0.001	-0.46	0.17	0.010
U6H	0.06	0.70	0.578	-0.14	0.46	0.183	0.20	0.16	0.240
PP_MP	0.02	1.13	0.905	0.17	1.03	0.454	-0.15	0.29	0.609
LFH	0.52	0.93	0.001	0.79	0.85	<0.001	-0.27	0.24	0.261
TFH	0.80	0.99	<0.001	0.74	0.93	0.001	0.06	0.25	0.817

Bold font indicates significant difference.