Table 7.
Comparative all-cause mortality data for TPE in MG.
| Reference | Treatment context | Comparison | Timing | # Patients | Mortality (%) | P -value ∧ |
|---|---|---|---|---|---|---|
| Lal et al. (54) | Acute | TPE/No TPE** | hosp. | 4/3 | 0/100% | 0.03 |
| Berrouschot et al. (53) | Acute | TPE/No TPE** | 3 mo | 21/42 | 19/10% | 0.42 |
| Gajdos et al. (41) | Acute | TPE/IVIG | 15 days | 41/46 | 0/0% | 1.00 |
| Barth et al. (5) | Acute | TPE/IVIG | 30 days | 41/40 | 0/0% | 1.00 |
| Pittayanon et al. (50) | Acute | TPE/IVIG | hosp. | 21/9 | 0/0% | 1.00 |
| Qureshi et al. (42) | Acute | TPE/IVIG | hosp. | 24/27 | 4/7% | 1.00 |
| Murthy et al. (47) | Acute | TPE/IVIG | hosp. | 15/8 | 7/13% | 1.00 |
| Guptill et al. (44) | Acute | TPE/IVIG | hosp.* | 72/31 | 0/0% | 1.00 |
| Köhler et al. (52) | Acute | TPE/IA | 180 days | 10/9 | 10/0% | 1.00 |
| Schneider-Gold et al. (51) | Acute | TPE/IA | hosp. | 19/24 | 0/0% | 1.00 |
| Trikha et al. (65) | Acute | TPE QD/TPE QAD | hosp. | 16/17 | 13/6% | 0.59 |
| Rønager et al. (45) | Chronic | TPE/IVIG | 16 wk | 12/12 | 0/0% | 1.00 |
| Liew et al. (25) | Chronic | TPE/IVIG | 1 yr* | 17/20 | 0/0% | 1.00 |
| Sarkar et al. (55) | Peri-operative | TPE/No TPE | 1 yr | 10/9 | 0/0% | 1.00 |
| Saeteng et al. (56) | Peri-operative | TPE/No TPE | hosp. | 33/53 | 3/2% | 1.00 |
| Nagayasu et al. (10) | Peri-operative | TPE/No TPE | 116 mo* | 19/32 | 0/6% | 0.52 |
| El-Bawab et al. (64) | Peri-operative | TPE all pts/TPE selective | hosp. | 74/90 | 0/0% | 1.00 |
| Mandawat et al. (1) | Mixed | TPE/IVIG | hosp. | 1,269/340 | 3/1% | 0.21∧∧ |
| Guptill et al. (62) | Mixed | TPE peripheral/TPE central | treatment | 100/34 | 0/6% | 0.07 |
| Mandawat et al. (63) | Mixed | TPE early/TPE delayed | hosp. | 870/183 | 1/7% | <0.0001 |
| Rock et al. (69) | NS | TPE pentastarch/TPE albumin | Not specified | 4/3 | 0/0% | 1.00 |
hosp., during hospitalization; QD, daily; QAD, every other day; lA, immunoadsorption; NS, not specified* Timing: (44) through hospitalization or later, (25) median 1 yr follow-up (range 0–5 yrs), (10) mean 116 mo for all patients (100.2 ± 41.2 mo TPE vs. 125.1 ± 77.5 mo No TPE).
∧
Calculated by report authors using Fisher's exact test unless otherwise noted.
∧∧
P-value for adjusted odds ratio as reported by original study authors.