Table 1.

Result of metabolic pathway analysis of the altered metabolites in GDM male offspring.

No.	Pathway name	Total	Hits	Raw P	Log(P)	Impact
1	D-Glutamine and D-glutamate metabolism	5	3	0.00882	4.7308	1
2	Alanine, aspartate, and glutamate metabolism	24	10	4.87E-05	9.9297	0.80168
3	Histidine metabolism	15	6	0.00229	6.0791	0.60753
4	Arginine and proline metabolism	44	11	0.003247	5.7302	0.51119
5	Cysteine and methionine metabolism	27	7	0.014986	4.2007	0.33775
6	Purine metabolism	68	14	0.006374	5.0555	0.32368
7	Citrate cycle (TCA cycle)	20	6	0.011535	4.4624	0.31799
8	Glutathione metabolism	26	6	0.041116	3.1914	0.20037
9	Aminoacyl-tRNA biosynthesis	69	15	0.002724	5.9056	0.12903

Total is the number of compounds involved in the pathway.

Hits is the actually matched number from the user uploaded data.

The raw P is the original P value calculated from the enrichment analysis.

Impact value is calculated from pathway topology analysis for comparison between different pathways.