Table 1.

Associations between the two miRNAs and clinical features

Variables	Numbers	miR-451a	P-value	miR-16-1-3p	P-value
Patient age at diagnosis
≤60	89	9.22 ± 1.23	0.98	2.54 ± 0.59	0.33
>60	40	9.23 ± 1.49		2.66 ± 0.64
Clinical stage（AJCC）
SI–II	79	9.39 ± 1.28	0.07	2.53 ± 0.57	0.30
SIII–IV	50	8.96 ± 1.32		2.65 ± 0.66
T stage (AJCC)
T1–2	69	9.36 ± 1.42	0.20	2.52 ± 0.50	0.22
T3–4	60	9.06 ± 1.16		2.65 ± 0.70
N stage (AJCC)
N0 & Nx	60	9.20 ± 1.38	0.87	2.54 ± 0.58	0.47
N1	69	9.24 ± 1.26		2.61 ± 0.63
M stage (AJCC)
M0 & Mx	126	9.25 ± 1.31	0.19	2.57 ± 0.61	0.38
M1	3	8.25 ± 1.22		2.88 ± 0.56
Histologic type
TPC	125	9.21 ± 1.32	0.48	2.57 ± 0.60	0.12
Non TPC	4	9.68 ± 0.82		2.81 ± 0.80
Tumour location
One lobe	97	9.15 ± 1.26	0.32	2.63 ± 0.55	0.12
More than one lobe	32	9.42 ± 1.46		2.43 ± 0.73