Homan 1969.
Methods | Stratified random allocation; double‐blind (A); placebo‐controlled; 19% drop out after 1.7 years (study duration = 1.7 years). Reasons for attrition not described; any differential group losses not assessable. | |
Participants | 1874 children analysed at 1.7 years. Age range at start: 7‐13 years. Surfaces affected at start: data not available nor obtainable. Background exposure to fluoride: none. Year study began: 1965. Location: Australia. | |
Interventions | FT (3 groups) versus PL
(SnF2 and APF toothpaste concentrations NR nor obtainable). Home use/unsupervised, daily frequency assumed. Abrasive system: Ca pyrophosphate in one SnF2 toothpaste, calcium‐free abrasive in the other SnF2 toothpaste and in the APF toothpaste; abrasive in placebo toothpaste NR. |
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Outcomes | Caries increment data NR (not obtainable). Percentage DFS reductions by gender and age groups reported at 1.7 years follow up. |
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Notes | Participants randomised (N = 2317); numbers by group NR. Baseline characteristics NR. Clinical (VT) caries assessment by two examiners; diagnostic threshold = CA; state of tooth eruption included = E; radiographic assessment; diagnostic threshold = DR. Diagnostic errors NR. | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Allocation concealment (selection bias) | Low risk | A ‐ Adequate |