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. 2003 Jan 20;2003(1):CD002278. doi: 10.1002/14651858.CD002278

Homan 1969.

Methods Stratified random allocation; double‐blind (A); placebo‐controlled; 19% drop out after 1.7 years (study duration = 1.7 years). Reasons for attrition not described; any differential group losses not assessable.
Participants 1874 children analysed at 1.7 years.
 Age range at start: 7‐13 years. 
 Surfaces affected at start: data not available nor obtainable.
 Background exposure to fluoride: none.
 Year study began: 1965.
 Location: Australia.
Interventions FT (3 groups) versus PL
 (SnF2 and APF toothpaste concentrations NR nor obtainable).
Home use/unsupervised, daily frequency assumed.
 Abrasive system: Ca pyrophosphate in one SnF2 toothpaste, calcium‐free abrasive in the other SnF2 toothpaste and in the APF toothpaste; abrasive in placebo toothpaste NR.
Outcomes Caries increment data NR (not obtainable).
Percentage DFS reductions by gender and age groups
 reported at 1.7 years follow up.
Notes Participants randomised (N = 2317); numbers by group NR.
 Baseline characteristics NR.
 Clinical (VT) caries assessment by two examiners; diagnostic threshold = CA; state of tooth eruption included = E; radiographic assessment; diagnostic threshold = DR. Diagnostic errors NR.
Risk of bias
Bias Authors' judgement Support for judgement
Allocation concealment (selection bias) Low risk A ‐ Adequate
HHS Vulnerability Disclosure