Table 2.

Primary and secondary outcomes

Outcomes	NIV (N = 110)	HFNC (N = 112)	Relative risk (95% CI)	P
Primary outcomes, No. (%)
Reintubation at 72 h	20 (18.2)	20 (17.9)	0.99 (0.70–1.39)	0.95
Secondary outcomes, No. (%)
Reintubation at 7 days	30 (27.3)	24 (21.4)	0.86 (0.64–1.14)	0.31
Reintubation at 28 days	40 (36.4)	37 (33.0)	0.93 (0.71–1.22)	0.6
Reintubation in ICU	37 (33.6)	33 (29.5)	0.91 (0.69–1.19)	0.5
Extubation failure at 72 h	34 (30.9)	27 (24.1)	0.85 (0.64–1.12)	0.26
Extubation failure in ICU	47 (42.7)	37 (33.0)	0.82 (0.63–1.06)	0.14
Mortality
ICU mortality	12 (10.9)	6 (5.4)	0.72 (0.51–1.03)	0.13
28-day mortality	10 (9.1)	8 (7.1)	0.88 (0.57–1.37)	0.59
In-hospital mortality	26 (23.6)	24 (21.4)	0.94 (0.69–1.28)	0.69
Length of stay, median (IQR), days
ICU length of stay	10 (6–22)	10 (6–19)		0.68
Hospital length of stay	24 (14–44)	28 (19–48)		0.23