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. 2021 Sep 14;11:135. doi: 10.1186/s13613-021-00922-5

Table 3.

Duration of device usage and causes of reintubation

Variables NIV
(N = 110)
HFNC
(N = 112)
Relative risk
(95% CI)
P
Duration of device usage, median (IQR), h 24 (19–42) 24 (20–55) 0.18
Interval from extubation to reintubation, median (IQR), h 67 (23–139) 54 (19–282) 0.90
Device protocol compliance rate 105 (95.5) 107 (95.5) 0.99 (0.49–2.01) 0.98
Causes of reintubation, No. (%)
 Hypoxia 21 (19.1) 20 (17.9) 0.96 (0.69–1.34) 0.81
 Hemodynamic instability 6 (5.5) 4 (3.6) 0.82 (0.48–1.38) 0.50
 Cardiac arrest 4 (3.6) 4 (3.6) 0.99 (0.49–2.01) 0.98
 Urgent surgery 2 (1.8) 1 (0.9) 0.74 (0.33–1.67) 0.55
 Inability to clear secretions 1 (0.9) 4 (3.6) 2.51 (0.43–14.57) 0.18
 Altered mental status 1 (0.9) 4 (3.6) 2.51 (0.43–14.57) 0.18
 Others 2 (1.8) 1 (0.9) 0.65 (0.38–1.17) 0.50

Calculated using patients who required reintubation (37 in the NIV group and 33 in the HFNC group)

*Calculated using patients who required a device change (20 in the NIV group and nine in the HFNC group)