Table 2. Regional brain volume measurements (mm3) and their variation with age in WT and HSHA mice at 8, 12, and 18 months.
Brain regions | 8 months | 12 months | 18 months | |||
---|---|---|---|---|---|---|
WT | HSHA | WT | HSHA | WT | HSHA | |
Cerebral CTX | 172.51 ± 6.91 | 164.36 ± 7.41 | 158.16 ± 2.35 | 153.63 ± 8.45 | 172.95 ± 0.97 | 177.48 ± 8.36 |
HPF | 32.20 ± 3.82 | 26.93 ± 4.13 | 31.63 ± 1.61 | 23.58 ± 2.68 | 20.54 ± 0.36 | 22.94 ± 1.43 |
Ventriclesa | 20.20 ± 1.49 | 23.89 ± 3.01 | 20.15 ± 1.35 | 23.49 ± 3.22 | 20.19 ± 0.57 | 17.38 ± 1.75 |
Values are mean ± SEM; n = 2–3/group. The data underlying Table 2 can be found in S1 Data.
aTotal ventricle comprises the sum of the lateral, third, and fourth ventricle.
CTX, cortex; HPF, hippocampal formation; WT, wild-type.