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. 2021 Aug 26;17(8):e1009732. doi: 10.1371/journal.pgen.1009732

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Fig 2 — LocusZoom plots showing the regional genes surrounding a 1 mega base pair region around SNP rs1800566 on chromosome 16 for associations with erlotinib. In the top panel, SNPs rs12447326 and rs1800566 are both used as lead/reference SNPs (shown as diamonds). For all other non-lead SNPs (shown as circles and triangles), their color and shape are matched to the lead SNP with which it is in the highest linkage disequilibrium (LD), as shown in the legend. The extent of LD with the lead SNP is shown by the color gradient. In the bottom panel, SNP rs1800566 is used as the lead SNP, and all other SNPs are colored according to their level of LD with rs1800566, as shown in the legend.