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. 2021 Aug 26;17(8):e1009732. doi: 10.1371/journal.pgen.1009732

Fig 4. The three-stage protein QTL model used to identify the mechanism by which SNP rs1800566 influences drug response.

Fig 4

Stage 1: the association between SNP rs1800566 and drug response measured as AUC; Stage 2: the association between SNP rs1800566 and NQO1 protein activity; and Stage 3: the association between NQO1 protein activity and drug response.