Fig 7. Correlation of NQO1 mRNA expression and cell viability.

Increased cell viability was observed with higher levels of NQO1 mRNA expression as measured in 12 LCLs exposed to 0.5μM arsenic trioxide. The 12 selected LCLs comprise six sensitive and six resistant cell lines, classified based on their mean viability (AUC values) across the four drug treatments: arsenic trioxide, erlotinib, trametinib, and the paclitaxel + epirubicin combination. Each cell sample was measured in triplicate. The replicates were averaged for each cell line.