Table 6.

Association of the genotypes of two SNPs combined with environmental factors with the risk of gastric cancer: multivariate logistic regression analysis.

Risk Factors Combined With Genotypes	OR	95% CI	p-Value
rs4072037
Age > 60 + AA	1.57	1.05–2.34	0.03*
Male + AA	1.84	1.28–2.67	0.00*
Smoking + AA	1.72	1.11–2.67	0.02*
Alcohol abuse history + AA	2.06	1.32–3.23	0.00*
Personal history of gastritis + AA	1.31	0.89–1.91	0.16
Family history of gastric cancer + AA	6.47	2.21–18.89	0.00*
rs2070803
Age > 60 + GG	1.50	1.00–2.25	0.05*
Male + GG	1.80	1.25–2.63	0.00*
Smoking +GG	1.68	1.07–2.63	0.02*
Alcohol abuse history + GG	1.98	1.22–3.04	0.00*
Personal history of gastritis + GG	1.22	0.83–1.80	0.31
Family history of gastric cancer + GG	6.18	2.11–18.10	0.00*

OR, odds ratio; 95% CI, 95% confidence interval; SNP, single-nucleotide polymorphism.

*Significant at 0.05.