Table 3.
Primary and major secondary outcomes by preoperative diagnosis
| Outcome | Initial Laparotomy (N = 146) n/N (%) | Initial Drainage (N = 162) n/N (%) | Frequentist Adjusted Relative Risk (95% CI) | Bayesian Adjusted Relative Risk (95% CrI) | Bayesian Adjusted Risk Difference (95% CrI) | Bayesian Posterior Probability (%) of RD <0 with Laparotomy |
|---|---|---|---|---|---|---|
| Death or NDI | ||||||
| NEC | 29/42 (69%) | 44/52 (85%) | 0.81 (0.64, 1.04) | 0.81 (0.63, 1.00) | −14% (−31, 1) | 97 |
| IP | 68/99 (69%) | 64/102 (63%) | 1.11 (0.95, 1.31) | 1.09 (0.90, 1.33) | 6% (−7, 18) | 18 |
| Death | ||||||
| NEC | 17/42 (40%) | 27/53 (51%) | 0.77 (0.52, 1.13) | 0.82 (0.53, 1.20) | −11% (−30, 8) | 87 |
| IP | 24/104 (23%) | 21/109 (19%) | 1.28 (0.79, 2.06) | 1.18 (0.74, 1.87) | 5% (−7, 20) | 20 |
| Survival with NDI | ||||||
| NEC | 12/42 (29%) | 17/52 (33%) | 0.73 (0.42, 1.27) | 0.76 (0.48, 1.18) | −19% (−45, 7) | 92 |
| IP | 44/99 (44%) | 43/102 (42%) | 1.11 (0.85, 1.45) | 1.08 (0.83, 1.42) | 5% (−10, 20) | 26 |
| Death or moderate to severe cerebral palsy | ||||||
| NEC | 22/42 (52%) | 38/52 (73%) | 0.70 (0.47, 1.05) | 0.73 (0.52, 0.96) | −18% (−38, −2) | 99 |
| IP | 36/100 (36%) | 41/105 (39%) | 0.95 (0.76, 1.19) | 0.95 (0.68, 1.32) | −2% (−16, 12) | 62 |
| Death or Bayley cognitive composite score < 85 | ||||||
| NEC | 28/42 (67%) | 41/50 (82%) | 0.81 (0.61, 1.06) | 0.80 (0.61, 1.01) | −13% (−32, 2) | 96 |
| IP | 67/99 (68%) | 59/101 (58%) | 1.17 (1.01, 1.37) | 1.15 (0.94, 1.42) | 9% (−4, 22) | 8 |
*
Denominators in each cell reflect the number of infants with complete data for each outcome reported