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. Author manuscript; available in PMC: 2021 Sep 14.
Published in final edited form as: J Allergy Clin Immunol. 2014 May 3;134(3):737–739.e6. doi: 10.1016/j.jaci.2014.03.028

TABLE I.

Sensitivity, Specificity, Positive Predictive Value (PPV), Negative Predictive Value (NPV)* and Area Under the Receiver Operating Characteristics Curve (AUC) for Physician-Diagnosed AR and Various Predictive Models.

Sensitivity Specificity PPV NPV AUC (95% CI)
Physician-Diagnosed AR – Model A
 Asthma 22.9% 94.8% 89.8% 38.1% 0.59 (0.55–0.63)
 No Asthma 12.3% 98.9% 81.8% 74.2% 0.56 (0.52–0.59)
 All 20.0% 97.5% 88.3% 56.5% 0.59 (0.56–0.61)
Rhinitis Symptoms Only – Model B
 Asthma 100.0% 54.2% 81.4% 100.0% **
 No Asthma 100.0% 86.6% 74.5% 100.0% **
 All 100.0% 75.5% 79.3% 100.0% **
Rhinitis Symptoms and Dust Mite-IgE – Model C
 Asthma 72.6% 75.5% 85.7% 57.7% 0.74 (0.69–0.79)
 No Asthma 67.1% 95.1% 83.9% 88.3% 0.81 (0.75–0.87)
 All 71.2% 88.5% 85.3% 76.6% 0.80 (0.76–0.83)
Rhinitis Symptoms and (Dust Mite-IgE and/or Cockroach IgE) – Model D
 Asthma 75.8% 73.4% 85.2% 60.0% 0.75 (0.69–0.80)
 No Asthma 68.6% 94.5% 82.8% 88.7% 0.82 (0.76–0.87)
 All 73.9% 87.4% 84.6% 78.1% 0.81 (0.77–0.84)
Rhinitis Symptoms and (Dust Mite-IgE and/or House Dust Trigger) – Model E
 Asthma 96.8% 53.2% 80.7% 89.3% 0.75 (0.70–0.80)
 No Asthma 88.6% 89.1% 75.6% 95.3% 0.89 (0.84–0.93)
 All 94.6% 76.9% 79.4% 93.8% 0.86 (0.83–0.89)
Rhinitis and Total IgE ≥ 100 kU/L – Model F
 Asthma 83.3% 70.8% 85.1% 68.0% 0.77 (0.72–0.82)
 No Asthma 76.7% 91.4% 77.8% 90.9% 0.84 (0.79–0.89)
 All 81.5% 84.4% 83.1% 82.9% 0.83 (0.80–0.86)
Rhinitis and (Total IgE ≥ 100 kU/L and/or House Dust Trigger) – Model G
 Asthma 97.9% 55.2% 81.4% 93.0% 0.77 (0.71–0.82)
 No Asthma 91.8% 87.6% 74.4% 96.5% 0.90 (0.86–0.94)
 All 96.2% 76.6% 79.4% 95.6% 0.86 (0.84–0.89)
Rhinitis and House Dust Trigger – Model H
 Asthma 90.1% 57.3% 80.8% 74.3% 0.74 (0.68–0.79)
 No Asthma 82.2% 90.3% 76.9% 92.8% 0.86 (0.81–0.91)
 All 87.9% 79.1% 79.8% 87.5% 0.84 (0.80–0.87)
*

Gold standard = STR-positive AR.

**

AUC unable to be calculated.