TABLE I.
Sensitivity | Specificity | PPV | NPV | AUC (95% CI) | |
---|---|---|---|---|---|
Physician-Diagnosed AR – Model A | |||||
Asthma | 22.9% | 94.8% | 89.8% | 38.1% | 0.59 (0.55–0.63) |
No Asthma | 12.3% | 98.9% | 81.8% | 74.2% | 0.56 (0.52–0.59) |
All | 20.0% | 97.5% | 88.3% | 56.5% | 0.59 (0.56–0.61) |
Rhinitis Symptoms Only – Model B | |||||
Asthma | 100.0% | 54.2% | 81.4% | 100.0% | ** |
No Asthma | 100.0% | 86.6% | 74.5% | 100.0% | ** |
All | 100.0% | 75.5% | 79.3% | 100.0% | ** |
Rhinitis Symptoms and Dust Mite-IgE – Model C | |||||
Asthma | 72.6% | 75.5% | 85.7% | 57.7% | 0.74 (0.69–0.79) |
No Asthma | 67.1% | 95.1% | 83.9% | 88.3% | 0.81 (0.75–0.87) |
All | 71.2% | 88.5% | 85.3% | 76.6% | 0.80 (0.76–0.83) |
Rhinitis Symptoms and (Dust Mite-IgE and/or Cockroach IgE) – Model D | |||||
Asthma | 75.8% | 73.4% | 85.2% | 60.0% | 0.75 (0.69–0.80) |
No Asthma | 68.6% | 94.5% | 82.8% | 88.7% | 0.82 (0.76–0.87) |
All | 73.9% | 87.4% | 84.6% | 78.1% | 0.81 (0.77–0.84) |
Rhinitis Symptoms and (Dust Mite-IgE and/or House Dust Trigger) – Model E | |||||
Asthma | 96.8% | 53.2% | 80.7% | 89.3% | 0.75 (0.70–0.80) |
No Asthma | 88.6% | 89.1% | 75.6% | 95.3% | 0.89 (0.84–0.93) |
All | 94.6% | 76.9% | 79.4% | 93.8% | 0.86 (0.83–0.89) |
Rhinitis and Total IgE ≥ 100 kU/L – Model F | |||||
Asthma | 83.3% | 70.8% | 85.1% | 68.0% | 0.77 (0.72–0.82) |
No Asthma | 76.7% | 91.4% | 77.8% | 90.9% | 0.84 (0.79–0.89) |
All | 81.5% | 84.4% | 83.1% | 82.9% | 0.83 (0.80–0.86) |
Rhinitis and (Total IgE ≥ 100 kU/L and/or House Dust Trigger) – Model G | |||||
Asthma | 97.9% | 55.2% | 81.4% | 93.0% | 0.77 (0.71–0.82) |
No Asthma | 91.8% | 87.6% | 74.4% | 96.5% | 0.90 (0.86–0.94) |
All | 96.2% | 76.6% | 79.4% | 95.6% | 0.86 (0.84–0.89) |
Rhinitis and House Dust Trigger – Model H | |||||
Asthma | 90.1% | 57.3% | 80.8% | 74.3% | 0.74 (0.68–0.79) |
No Asthma | 82.2% | 90.3% | 76.9% | 92.8% | 0.86 (0.81–0.91) |
All | 87.9% | 79.1% | 79.8% | 87.5% | 0.84 (0.80–0.87) |
Gold standard = STR-positive AR.
AUC unable to be calculated.