Figure 2.

Heatmap of the top 50 most abundant amplicon sequence variants (ASVs), clustered at the level of species if possible. Taxonomy shown is the identified genus, and the most closely related species, if known. Samples are averaged into primary phases of the CHIM for each study participant, including pre-challenge, inpatient, post-ciprofloxacin/azithromycin administration, and post-discharge. Samples are shown faceted by treatment group; among those study participants either receiving placebo or rifaximin prophylaxis. Gray squares indicate an ASV was not detected. For clarification on sample phase definitions (pre-challenge, inpatient, post-challenge, etc.), please see Figure 1. Heatmap scale is log₁₀.